ESPN College Football

1. Florida State's young offensive line against Georgia Tech's veteran defensive line. The game will be won or lost here. The Seminoles will need their best run blocking effort considering that's the foundation of their offense.

2. Florida State running backs Antone Smith and Jermaine Thomas. They both expect to play, but their health, especially Smith's, will be key to winning the football game. Smith had injured his ribs and elbow, and Thomas had a concussion.

3. Georgia Tech's quarterbacks. Paul Johnson has said this week he might play both Josh Nesbitt and Jaybo Shaw, but if Nesbitt is able to limit his turnovers, he might not have to. The better protection the line gives him, the less likely he is to be forced into a mistake.

4. Clemson running back C.J. Spiller. The dynamic return man will play at Boston College after missing the past seven quarters with an injured hamstring, but how much of a boost can he give a running game that combined for just 72 rushing yards in the past two games?

5. Turnovers in Chestnut Hill. It's something Boston College coach Jeff Jagodzinski has been talking about all week, as his Eagles have now surrendered the ball eight times in their past two games. But they're not the only ones. Clemson turned it over six times in its loss to Georgia Tech.

6. Miami's run defense. It hasn't been entirely convincing this season, giving up 113.9 yards per game and 10 touchdowns. The Hurricanes will have to give their best effort in order to slow Virginia running back Cedric Peerman.

7. Bowl eligibility. Only Maryland and North Carolina are bowl eligible, but Florida State, Miami, Boston College, Georgia Tech and Virginia can change that this week. Problem is, half of 'em are playing each other.

8. Wake Forest's ability to create turnovers. In the first three games of the season, Wake secured 15 takeaways (five at Baylor, three against Ole Miss and seven at Florida State). They were undefeated and No. 15 in the nation. In the past four games, they have only five takeaways. It's no coincidence they've lost three of the past four.

9. The Demon Deacons' ability to create offense. For six games they tried a spread offense. For their seventh they lined up in the I-formation. This game they'll probably mix it up, but will it work?

10. Clash of the Coastal in Charlottesville. Virginia has won 15 of its past 17 homecoming games and needs to win this one in order to stay atop the Coastal Division standings. But Miami needs to win in order to say in the mix. If the Hurricanes pull off the road win, get ready for some confusion in the Coastal.