David Ortiz hits 509th homer to power Red Sox past White Sox

Ortiz hits go-ahead homer for Red Sox (0:22)

Red Sox DH David Ortiz takes White Sox pitcher Carlos Rodon deep to right field for a go-ahead two-run home run in the fifth inning. It's Ortiz's sixth home run of the season and the 509th of his career. (0:22)

CHICAGO -- David Ortiz hit his 509th home run to put the Boston Red Sox ahead to stay in a 5-2 victory over the Chicago White Sox on Wednesday night.

Ortiz's two-run shot to right field off Carlos Rodon in the fifth inning tied him with Gary Sheffield for 25th all-time. It was his sixth homer of the season and 451st with Boston, one off Carl Yastrzemski's club mark.

Ortiz added an RBI single in the seventh against Zach Duke, and embattled Clay Buchholz (1-3) was sharp over seven innings in Boston's fourth win in five games.

Jose Abreu's two-run homer in the first was the only blemish for Buchholz, who allowed three hits and struck out six.