The rest day will give players a chance to recover from two padded practices at St. Vincent College. Luckily for the Bills, they came out of the sessions with no apparent injuries. For this point in camp, the team is relatively healthy.
Here is a look at which players may not suit up Saturday night:
Cordy Glenn: The 345-pound left tackle has yet to be cleared for team drills. He took part in one-on-one pass-rushing drills in both joint practices this week, signaling that he's progressing as he returns from the non-football illness list. Still, don't expect him to be in uniform Saturday.
Leodis McKelvin: Will McKelvin see his first preseason action Saturday? It's possible, but not likely. The Bills have been cautious with McKelvin since he sat out organized team activities (OTAs) recovering from hip surgery. He was in uniform in Latrobe this week, a step forward from his status the week prior.
Tony Moeaki: It has to be a frustrating training camp for Moeaki, who battled injuries in Kansas City and had a chance for a significant role in the Bills' offense before being sidelined with a hamstring injury. He returned to practice on a limited basis last week and saw a few snaps at the end of the Bills' preseason win over the Carolina Panthers, but he wasn't in uniform this week. Moeaki spent both joint practices working with the strength and conditioning staff.
Marquise Goodwin: Here's another player who can't seem to shake injury issues. Goodwin played 12 snaps in last Friday's preseason win but looks to be dealing with a nagging hamstring injury, as he was out of practice again this week. It doesn't necessarily signal a setback -- the Bills may want to rest him -- but given the competition at receiver, Goodwin could benefit from being on the field and healthy. In his first 16 months with the Bills, that's been a problem.
Chris Williams: Williams hasn't practiced since he played 44 snaps in Friday's preseason win. He's listed with a lower back injury and watched practices this week from the sidelines. Doug Marrone said he doesn't have any "long-term" concerns about Williams' injury, but I wouldn't expect to see him play Saturday.
Jonathan Meeks: The second-year safety looks to have fallen behind Duke Williams, who was drafted a round ahead of him last year, in the safety battle. A neck injury last week hasn't helped Meeks' case. He didn't practice this week and isn't expected to play Saturday.
Ty Powell: The Bills could have a few open roster spots at linebacker following Kiko Alonso's injury and Nigel Bradham's one-game suspension, and Powell remains in that mix. However, he's been sidelined since last weekend with a "medical" issue. He watched practice from the sidelines this week in Latrobe.
Dustin Hopkins: Hopkins sat out practices in Latrobe this week with a groin injury. That could be a bit of a red flag for Hopkins, who Marrone said must make the roster as a kickoff specialist -- he isn't competing with Dan Carpenter to kick field goals. Hopkins missed all of last season with a groin injury.
Two other players to keep an eye on: running backs Bryce Brown and Anthony Dixon. After taking a hit during a live tackling drill Thursday, trainers and a team doctor examined Brown's rib area. He later returned to practice. Meanwhile, WGR 550's Joe Buscaglia said Dixon was also examined by the medical staff at the end of Thursday's practice.