ESPN NFL

Posted by ESPN.com's Tim Graham

The Buffalo Bills' offensive line, so impressive through the first two games despite their inexperience, suffered a devastating blow during Sunday's victory over the Tampa Bay Buccaneers.

The Bills have announced right tackle Brad Butler will miss the rest of the season because of a knee injury.

The Bills went into the season with paltry 56 career starts among their five starting offensive linemen. Butler had 29 of them.

Maybe it's the Jason Peters Curse.

Butler moved from right guard to right tackle as part of the Bills' massive offseason O-line overhaul triggered by the trade that sent two-time Pro Bowl left tackle Jason Peters to the Philadelphia Eagles. Langston Walker, last year's right tackle and the team's most experienced lineman at the time, was moved to left tackle.

But the Bills cut Walker a week before the season began, making Butler the most experienced offensive lineman. Now the greybeard is center Geoff Hangartner, who is up to 29 career starts after two games with Buffalo.

Three Buffalo offensive linemen -- left tackle Demetrius Bell, guards Eric Wood and Andy Levitre -- made their NFL debuts on opening night.

Jonathan Scott, who made six NFL starts for the Detroit Lions in 2006 and 2007, replaced Butler for the rest of Sunday's game.

If they don't sign any outside help (they tried out veteran right tackle Jon Runyan on Sept. 11), the Bills will have a combined 51 starts on their line heading into their Week 3 matchup with the New Orleans Saints.