Will Lacey be at nickel for Jackson Sunday night?

Posted by ESPN.com’s Paul Kuharsky

The Colts have done a great job so far this season mixing and matching in the secondary and indications are they will need to do it some more Sunday night in Nashville.

Marlin Jackson, who’s only played nickel so far as he returns from a torn ACL, tweaked his knee and hasn’t practiced this week. Here’s John Oehser’s write-up of the situation.

Starter Kelvin Hayden said this week he expects to miss one more game and return after the bye. If Jackson is also out, that means rookie Jerraud Powers and Tim Jennings as the starters for the third week in a row, with undrafted rookie Jacob Lacey plugged into the nickel package.

The Titans' third receiver is rookie Kenny Britt, but he doesn’t automatically line up in the slot. Tennessee is comfortable moving starters Justin Gage, Nate Washington and Britt around based on matchups they find favorable.

Left tackle could be an issue for the Colts as well. Starter Charlie Johnson’s been out since injuring a knee against Seattle. Dan Federkeil, not Tony Ugoh, was the backup against the Seahawks.

Coach Jim Caldwell tried to soft-pedal Ugoh’s status for that game, citing an unidentified “nick” that prompted the team to make Ugoh inactive, but Ugoh never appeared on the injury report.

Federkeil or Ugoh could be a good draw for Tennessee defensive end Kyle Vanden Bosch, a great motor guy who’s feeling a lot of pressure after going without a sack in the first quarter of the season.