Pre-game thoughts from San Diego

Posted by ESPN.com's Bill Williamson

SAN DIEGO - Some pre-game notes prior to the Colts-Chargers game:

The weather for San Diego tonight is expected to be mild with temperatures hovering around 60 degrees.

San Diego defensive lineman Luis Castillo is inactive. He suffered a groin injury last week in Pittsburgh. Jacques Cesaire will take his place in the starting lineup. Castillo was expected to miss the game after he didn't practice all week.

Melvin Bullitt will start for the injured Bob Sanders at strong safety for the Colts. Sanders didn't make the trip with a knee injury. It is the second straight missed game for the reigning NFL Defensive Player of the Year.