The injury appeared to happen with about 1:17 left in the first quarter when Floyd was hit by Houston Texans cornerback Kareem Jackson after a 20-yard catch. He stayed in for the rest of the quarter, but asked for a sub as the quarter broke.
After Sunday’s 27-24 win against the Texans, Arians thought Floyd would be ready for next week against Jacksonville, but his tune changed Monday afternoon.
"At first it looked like just a bruised shoulder but I don’t know the difference between a bruise and a sprain," Arians said. "I think he's going to want to play. That’s a big part of it.
"If he can't play it's a big blow because he's starting to break out."
Floyd is second on the Cardinals with 464 yards on 36 receptions. Arians expected Floyd to have a "big-time" game against the Texans because at 6-foot-2, 220 pounds, he creates matchup problems for secondaries.
"He's doing such a good job in the running game that it's helping him in the passing game to dictate some coverages," Arians said.