Posted by ESPN.com's Adam Rittenberg

If Iowa's depth chart is any indication, the Hawkeyes' offense could be fighting an uphill battle on Saturday night at No. 5 Penn State (ABC, 8 p.m. ET).

Left tackle Bryan Bulaga, tight end Tony Moeaki and wide receiver Derrell Johnson-Koulianos are all absent from the two-deep issued Monday. Bulaga has missed the last two games with an undisclosed illness, while the oft-injured Moeaki missed the Arizona game with an ankle problem. Johnson-Koulianos, the team's leading wideout the last two seasons, is dealing with a hamstring injury.

Head coach Kirk Ferentz addresses the media Tuesday, but here's what he had to say about the injury situation after Saturday's game.

Any chance all three of those guys could play next week?

Ferentz: There's a chance; I don't know if it's a good chance. I hope it's a good chance.

Doesn't sound too optimistic.

Redshirt freshman Riley Reiff would get the start at left tackle if Bulaga can't play. Allen Reisner and Brad Herman would handle things at tight end, and Paul Chaney Jr. would play a bigger role in the passing game if Johnson-Koulianos is unavailable.