Rookie defenseman Matt Bartkowski, who has played well in the playoffs, is a healthy scratch.
Ference suffered a lower-body injury in Game 5 of the quarterfinals against the Toronto Maple Leafs and has not played since.
Ference has been skating all week and participated in the pregame warmups, showing no ill effects, so Bruins coach Claude Julien decided to go with the veteran presence.
It appeared that would allow Julien to use his preferred defensive pairing of Zdeno Chara and Dennis Seidenberg. Ference will play with Johnny Boychuk, while Torey Krug and Adam McQuaid will be a pair.