Rapid Reaction: Diamondbacks 5, Cubs 4

PHOENIX -- The Chicago Cubs (40-55) opened the second half of the season with a 5-4 loss to the Arizona Diamondbacks (41-56) at Chase Field on Friday. Here's a quick look at the game:

How it happened: Arizona overcame a 3-0 deficit by scoring a pair of runs in the fifth inning and three more in the sixth. Chicago chased Arizona starter Trevor Cahill after five innings, but Cubs starter Edwin Jackson lasted just 5⅓ innings himself. Gerardo Parra's sacrifice fly in the sixth scored what proved to be the winning run.

What it means: The Cubs have lost three in a row and nine of their past 12 games. They have two more games in Arizona before returning to Wrigley Field for a 10-game homestand beginning Tuesday.

Rizzo rising: Anthony Rizzo hit two home runs and drove in three runs. His first blast gave Chicago a 2-0 lead and paced a three-run fourth inning. He added another in the sixth, giving him 22 homers on the year and putting the All-Star first baseman just one dinger away from his career high of 23 in 160 games last season. Rizzo is tied for fourth in the majors in home runs.

What's next: These teams will hook up for the second of this three-game series at Chase Field on Saturday at 7:10 p.m. CT. Left-hander Travis Wood (7-8, 4.96 ERA) is scheduled to start for Chicago. Lefty Wade Miley (5-6, 4.18) is slated to take the hill for Arizona.