Rapid Reaction: Phillies 4, Cubs 2

CHICAGO -- A quick look at the Chicago Cubs' 4-2 loss to the Philadelphia Phillies on Tuesday night at Wrigley Field.

How it happened: Sean Marshall gave up three runs in relief of Cubs starter Matt Garza, who had handled a tough Phillies lineup with ease. Garza allowed just four hits in seven-plus innings, including a double and a single to Domonic Brown. Garza was replaced by Marshall after Jimmy Rollins' base hit in the eighth and the Phillies tied the game that inning on Chase Utley's two-run double. Michael Martinez got the game-winning RBIs in the ninth. Cubs shortstop Starlin Castro hit his first home run since June 20.

What it means: The Cubs still haven’t won a series since a four-game set against the Brewers on June 13-16..

Outside the box: Third baseman Aramis Ramirez told ESPNChicago.com that he’d be interested in extending his contract past its current end point of 2012.

What’s next: Ryan Dempster (7-6, 4.68) will face the Phillies Vance Worley (5-1, 2.15) on Wednesday at 1:20 p.m. CT.