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Rapid Reaction: Astros 8, White Sox 3

CHICAGO -- Here's a quick look at the White Sox's first interleague play defeat of the season against the Houston Astros on Friday night.

How it happened: The White Sox began the second round of interleague play against the Astros, a team they had not played since 2007. RHP Gavin Floyd had been in a recent funk entering the game with a 11.90 ERA in his previous four starts. Once again homers hurt Floyd and the White Sox early. Brett Wallace hit a solo shot in the second inning, and Jed Lowrie hit a two-run bomb in the 5t . Lowrie also had a sacrifice fly that scored Houston’s first run in the first. Floyd struck out nine hitters in six innings of work.

The White Sox scored their first run in the 5th off starter Wandy Rodriguez. Alejandro DeAza doubled and eventually was plated on Adam Dunn’s groundout .The Sox scored two runs in the 6th sending Rodriguez to the showers. A.J. Pierzynski and Alexei Ramirez each had RBI hits in that frame. Houston sealed the deal on Brian Bogusevic’s three-run bomb in the top of the 9th.

What it means: The Sox are now 3-1 during interleague play in 2012. With the loss, the White Sox’s lead on the Cleveland Indians in the AL Central dropped to just half a game.

Outside the box: White Sox’s chairman Jerry Reinsdorf presented Ramirez with a replacement gold medal. The Cuban shortstop lost the original, which he won as a member of his country’s national team in the 2004 Athens Olympics.

Up next: Left-hander Chris Sale (7-2, 2.29 ERA ) tries to continue his recent dominance as he opposes Astros starter Jordan Lyles (1-1, 4.97 ERA) in a 3:10 start.