Rapid Reaction: Indians 7, White Sox 4

CLEVELAND -- The Chicago White Sox made it five consecutive defeats and eight losses in their last nine games after falling 7-4 on Tuesday to the Cleveland Indians.

How it happened: With Andre Rienzo in line for the victory in his first major league start, the White Sox bullpen gave up four runs in the eighth inning. Rienzo was solid in his major league debut allowing three runs, but none earned over seven innings. The right-hander ran into trouble in the fifth inning, and as has been a White Sox theme this season, the defense was to blame. An Alexei Ramirez fielding error, combined with the failure to turn a double play, led to the three unearned runs. The White Sox had a 3-0 lead after two innings on a two-run double from Adam Dunn and an RBI single from Josh Phegley.

What it means: Rienzo showed plenty in his debut, including a ton of energy, the desire to work quickly and the guts to pitch through pain (his right ankle was stepped on in the fifth inning). Most importantly, the 25-year-old right-hander showed an arsenal of pitches that can control major league bats, from a well-placed fastball in the low 90-mph range, to a slider and a developing changeup. Where the big stage can humble pitchers in their debut, Rienzo looked poised and confident.

Outside the box: The White Sox can’t avoid the injury bug. Jesse Crain was already traded with an injury. Jake Peavy missed extended time with a broken rib and has just made two starts since his return. Then in the eighth inning Tuesday, potential trade piece Alex Rios left the game during an at-bat after fouling a ball off his left foot.

Off beat: Tuesday’s game featured the first ever major league player from Brazil (Indians catcher Yan Gomes) against the second (Rienzo). In their first matchup, Gomes singled up the middle in the third inning. The next time they faced off in the fifth inning, Gomes walked with the bases loaded to pin the first ever run on Rienzo. The game was being televised live in Brazil.

Up next: The White Sox are tentatively scheduled to send Jake Peavy (8-4, 4.28 ERA) to the mound Wednesday at Cleveland in the third game of the four-game series. If Peavy is traded before the start, Jose Quintana (5-3, 3.55) is expected to take his place. The Indians will counter with right-hander Corey Kluber (7-5, 3.74) in the 6:05 p.m. (CST) start from Progressive Field.