Rapid Reaction: Astros 10, White Sox 8

CHICAGO -- Winners of four consecutive series, the Chicago White Sox stumbled 10-8 on Monday in the opener of a three-game set against the Houston Astros.

How it happened: Matt Dominguez hit a ninth-inning home run off Addison Reed to put the Astros ahead, and Chris Carter followed with his own dinger for some insurance. The White Sox loaded the bases in the bottom of the ninth, before Avisail Garcia struck out looking to end it. Carter hit two homers and had four RBIs on the night. The White Sox took the lead with a five-run sixth inning, but Carter tied it in the seventh on an RBI single. Andre Rienzo had the worst start of his young career, giving up seven runs on nine hits in six innings. Rienzo walked three and gave up three home runs in just his sixth start since being called up July 30.

What it means: In what was no doubt the sloppiest White Sox game of the season, the contest was littered with miscues on both sides. The Astros showed their inexperience in a number of ways, from Jonathan Villar getting picked off first base to L.J. Hoes dropping a fly ball on the warning track to David Martinez’s balk with a runner on third to tie the score 7-7. But the White Sox had plenty of their own issues that included Alejandro De Aza getting caught off third base on a comebacker; Garcia overrunning a ball in right to allow two runs to score; two wild pitches from Renzo that led to runs; and a misplay from De Aza in center.

Outside the box: Adam Dunn connected on his 30th home run of the season, the ninth time in his career that he has hit the 30-homer mark. Dunn also became the first White Sox left-handed hitter to record consecutive 30-homer seasons since Jim Thome did it three years in a row, from 2006 to 2008.

Offbeat: The White Sox were actually a major league best 8-1 since Aug. 16 before they were knocked off Monday by the worst team in league standings. The White Sox’s better play of late has included series victories over the first-place teams Detroit Tigers and Texas Rangers. Against the lowly Astros, though, the White Sox are 1-4, losing three of four games at Houston in June.

Up next: The White Sox will send left-hander Jose Quintana (7-4, 3.67 ERA) to the mound Tuesday in the middle game of the series. The Astros are undecided for a starter in the 7:10 p.m. CT start from U.S. Cellular Field.