Rapid Reaction: White Sox 3, Cubs1

CHICAGO -- The Chicago White Sox earned a marathon 3-1 victory in 12 innings Monday, their first over the Chicago Cubs since the 2012 season.

How it happened: Marcus Semien delivered the go-ahead run in the 12th on a double to score Alexei Ramirez, whose single was the 1,000th hit of his career. Semien has 16 RBIs, 15 of which have come in the sixth inning or later. Starters Jose Quintana of the White Sox and Jeff Samardzija of the Cubs were locked in a pitchers’ duel. Quintana allowed a run on one hit over seven innings, while Samardzija gave up an unearned run over nine innings. The White Sox scored in the first inning on a sacrifice fly from Jose Abreu, who was named player of the month and rookie of the month for April before the game.

What it means: The offense has subsided considerably after a hot opening month, essentially since leadoff man Adam Eaton was sidelined with a hamstring injury. Eaton can’t come back until May 18, so the White Sox are going to have to get creative with Alejandro De Aza and his .261 on-base percentage at the top of the order. Eaton last played Friday, and in the three games he missed entirely, the White Sox have scored seven runs, yet they won two of those three. They entered with 163 runs (5.09 per game), second in the major leagues.

Outside the box: Quintana retired the first 14 batters of the game, a run that ended when he walked Nate Schierholtz with two out in the fifth inning. He didn’t give up his first hit until the opposing pitcher doubled. Samardzija moved to second on a bunt and scored on a sacrifice fly. Quintana, who was allowed to throw 121 pitches in an April 13 start, was removed this time after 95.

Off beat: Manager Robin Ventura went with Adam Dunn in left, saying that the benefits of his slugger’s offense outweighed any deficiencies he might have in the outfield. Ventura forgot to calculate Dunn’s baserunning as well. On a Samardzija pitch that got away from Cubs catcher Welington Castillo in the fourth inning, Dunn didn’t break from third, even though the ball made it almost to the White Sox’s on-deck circle. He would have scored easily.

Up next: The White Sox will send right-hander Hector Noesi (0-1, 7.20) to the mound Tuesday in the second game of the two-game series. The Cubs will counter with right-hander Edwin Jackson (2-2, 5.24) in the 7:05 p.m. start from Wrigley Field.