King Felix gave up 10 hits in five innings and eight runs overall. He struck out four, walked one and hit a batter. He threw 92 pitches, 56 for strikes. Hernandez's next start is scheduled to come March 28, when the Mariners open the season against the Oakland Athletics in Tokyo.
The Mariners leave for Japan Thursday and will play two exhibition games there before the opener.
Left-hander Eric Stults gave up two runs and five hits for the White Sox. He struck out two and walked one in four innings.