How it happened: The Sox put three runs on the board in the first inning, courtesy of two home runs . Alejandro De Aza led off the game with his first career home run to start a game. A.J. Pierzynski's two-run blast also came off of Indians starter Josh Tomlin. However, the evening belonged to Chris Sale, who made his first professional start after spending the 2011 season in the bullpen.The 23-year-old left-hander did not allow his first run or second hit of the game until the sixth inning. Sale went 6 2/3 innings and threw 100 pitches.
What it means: The Sox are off to a good start in their division, where they play 20 of their first 37 games. The starting staff has given up just 12 runs in the first four games of the season. The South siders are now 2-2 on the road trip.
Outside the box: The team was silent in front of media members about former manager Ozzie Guillen’s predicament after he praised Fidel Castro in a magazine interview. Off the record, they were mostly surprised that things would blow up so early in Miami. Third baseman Brent Morel broke an 0-10 start to the season with an RBI single in the fifth inning. Morel had struck out six times in those 10 at-bats.