Chris Sale (2-1) struck out 11 in 6 1-3 innings. He gave up three runs and seven hits for the White Sox.
Dunn connected for a three-run homer off Hector Noesi (1-2) in the second inning to make it 6-0. He hit his third home run of the season in the eighth, giving him 31 multihomer games and the first since joining the White Sox last season, when he hit just 11 home runs. Friday was the first time Dunn had homered against Seattle in 12 career games.
Noesi lasted just 1 1-3 innings. He gave up six hits and six runs to send his ERA soaring to 9.49 from 5.73. Erasmo Ramirez pitched one-hit ball for 3 2-3 innings.