Santiago will start in place of Jake Peavy, who along with the rest of the rotation, gets an extra day between starts. The Sox are set up for the crucial final few games of the season against Cleveland and the Tampa Bay Rays with Peavy on Thursday, Jose Quintana on Friday and then most likely Gavin Floyd followed by Chris Sale.
“Most of this is getting the guys an extra day,” Ventura said. “Even watching Chris (Sale) (on Monday), he is at a different point than he has been at during his career. When we got him an extra day he has come back stronger.”
Santiago allowed one run in five innings to beat the Minnesota Twins in his first major league start on Sept. 3. He got a no-decision in his second start last week against the Kansas City Royals, striking out eight in four innings. Santiago started the season as the closer before losing the job to Addison Reed. Left-handed hitters are 4-for-42 against Santiago in his last 14 appearances.