Don't let them in the game: The Philadelphia Eagles should have no trouble with the Browns in Cleveland, but to a certain extent that appears to be up to them. According to ESPN Stats & Information, the Eagles ranked second in the league last year with 84 offensive plays of 20 or more yards, fourth in the league in total yards and fifth in yards per play. They were also eighth in total defense. So why were they 8-8? Their 38 turnovers were the second-most in the NFL. And nine of those turnovers were in the red zone. No other team in the league had more than five red-zone turnovers. If you want to lose to inferior teams, turnovers are the surest way. Watch the turnovers in Cleveland. If the Eagles commit a lot of them, the game could be much closer than most expect it to be. Working in Philadelphia's favor is that the Browns forced only 20 turnovers in 2011. Only seven teams forced fewer.
If Trent Cole outplays Joe Thomas, the Eagles will be well positioned to defeat the Browns on Sunday.
Marquee matchup: One of the Cleveland Browns' strengths is left tackle Joe Thomas, who was the No. 3 overall pick in the 2007 draft. He'll go up against Eagles defensive end Trent Cole, who has the third-most sacks in the NFL (63) since 2006, in a matchup that could go a long way toward deciding the game.
Road favorites? The Eagles should not be at a disadvantage just because the Browns are the home team in Sunday's game. Since this new incarnation of the Browns entered the league in 1999, it is 1-12 in season-opening games. The second-worst record in season openers over that same period of time is 4-9, shared by the Raiders and Chiefs.
Blowing in the Brees: If the Washington Redskins can hold New Orleans Saints quarterback Drew Brees without a touchdown pass, they'll have pulled off some trick. Brees has thrown at least one touchdown pass in each of his previous 43 games. That's the second-longest streak in NFL history behind the 47-game streak authored by Johnny Unitas from 1956-60. The Redskins will play this game without starting strong safety Brandon Meriweather, who is out with a knee injury, and safety Tanard Jackson, who is suspended for the year for violating the league's drug policy. They would do well to find a way to get some pressure on Brees.
Dome sweet dome: The Redskins are 6-1 all-time at the Louisiana Superdome, and while their most recent game there was in 2006, that record stands as a testament to the fact that the Redskins used to be one of the league's best teams and the Saints one of the league's worst. According to ESPN Stats & Information, Washington's .857 winning percentage at the Superdome is the highest in history for any team that has played at least five games there. Something has got to give, though. The Saints were 8-0 at home last year, and their 41.1 points per game and 492.6 yards per game there were the second-highest such home totals in NFL history.