Moore, who played at SMU, was signed by the Cowboys on Friday.
Nose tackle Jay Ratliff will miss his second consecutive game with a groin injury. He missed the first four games with an ankle injury and was inactive the last two weeks with the groin problem.
Ryan Cook will start at center, allowing Mackenzy Bernadeau to return to his natural right guard spot in the starting lineup. Bernadeau started at center in the last two games because of Cook's knee injury.
Eagles quarterback Michael Vick, wide receiver Greg Salas, running backs LeSean McCoy and Chris Polk, tackle/guard Nate Menkin and wide receiver Marvin McNutt are inactive for the Eagles. The Eagles have 52 players on their roster and will have six inactive.