Murray had to grind for his 4.2 yards per carry and failed to get one yard on a key fourth-down play in the fourth quarter.
Yet, if the Cowboys are going to rely on him in the big picture of things, they must find a way to get running lanes open for him. Sunday against the Cardinals, Murray didn't have quarterback Tony Romo (back) and two starters, left guard Ronald Leary (groin) and tackle Doug Free (foot).
If defenses try to stop Murray, they have to contend with Romo. But Arizona didn't care for his replacement, Brandon Weeden.
"It's probably the first time we [have] seen it and it probably won't be the last," Murray said of seeing seven- and eight-man defensive fronts.
Murray had just nine carries in the first half but the Cowboys went back toward him in the third quarter with eight touches, and with the game out of reach late in the fourth quarter the Cowboys had to throw the ball.
"Receivers get more catches they get into a rhythm and a quarterback throws more he gets into a rhythm and it goes on," Murray said. "As for myself and the offense line, it was hard to run the ball against those guys with 10 guys in the box. We need to make more plays."
It will get harder as the season progresses.
"We play great defense against the run and because we do have corners who can play man-to-man, we can put eight guys up there or seven up there," Arizona coach Bruce Arians said. "And our defensive line is penetrating, not sitting back and catching."