Pacquiao, along with trainer Freddie Roach, are back on American soil to finish Pacquiao's training camp for his welterweight title defense against junior welterweight titleholder Timothy Bradley Jr. on June 9 (HBO PPV), also at the MGM Grand.
With Mayweather-Cotto in the rearview mirror, that fight marks the next big date on the boxing calendar.
Pacquiao and Roach were greeted by a throng of fans when their Philippine Airlines Flight arrived. They will resume training on Monday at Roach's Wild Card Gym in Hollywood.
Pacquiao (54-3-2, 38 KOs), boxing's only eight-division champion, wasn't concerned about what was going with Mayweather-Cotto upon his arrival. Instead, he is looking forward to the fight with Bradley (28-0, 12 KOs).
"No matter what Bradley says, I still have the hunger to win," Pacquiao said, in reference to previous remarks made by Bradley. "I had a great camp in the Philippines. No distractions at all. We are ready to step it up over the next four weeks at Wild Card. This is a big fight for me. I can't wait for June 9."
Added Roach: "Maybe Bradley should come over to the Wild Card and see how hard Manny works in the ring. No one works harder -- no one -- and Manny is not ready to give up his throne. Manny is so serious. He gave up playing basketball, and that means a lot to him. He is a serious, dedicated athlete going into a very big fight. Now we do our finishing training at the Wild Card. I promise you Manny will shoot the works when he faces Bradley."