Timeline of Peyton Manning's key moments with the Indianapolis Colts

Ezra C. Shaw/Allsport

Peyton Manning’s 13-year career with the Indianapolis Colts was defined by success. He had just two losing seasons in the 12 years he played (Manning missed the 2011 season with a neck injury). Now that Manning has announced he is retiring, we look back on his impact while with the Colts:

April 18, 1998: The Colts selected Peyton Manning with the No. 1 overall pick over quarterback Ryan Leaf.

Sept. 6, 1998: Manning went 21-of-37 for 302 yards, a touchdown and three interceptions in his first NFL start, a 24-15 loss to the Miami Dolphins.

Jan. 16, 2000: Manning made his playoff debut, going 19-of-42 for 227 yards and no touchdowns in a 19-16 AFC divisional-round loss to the Tennessee Titans.

Dec. 26, 2004: Manning broke Dan Marino's single-season touchdown record when he threw his 49th touchdown pass to Brandon Stokley with 56 seconds remaining in regulation against San Diego.

Jan. 4, 2004: Manning won the first of his four Associated Press Most Valuable Player awards with the Colts, sharing the honor with Tennessee Titans quarterback Steve McNair. Manning threw for 4,267 yards and 29 touchdowns.

Jan. 18, 2004: Manning was 23-of-47 for one touchdown and four interceptions in a 24-14 loss to the New England Patriots in his first AFC Championship Game appearance.

Jan. 21, 2007: Manning finally got past Bill Belichick and the Patriots in the playoffs by beating them 38-34 in the AFC Championship Game.

Feb. 4, 2007: Manning won his first of two Super Bowls when he went 25-of-38 for 247 yards and a 53-yard touchdown pass to Reggie Wayne in the Colts’ 29-17 victory over the Chicago Bears.

Feb. 7, 2010: Manning threw a costly interception that was returned 74 yards for a touchdown by New Orleans Saints cornerback Tracy Porter late in the fourth quarter of the Colts’ 31-17 loss in Super Bowl XLIV.

Jan. 8, 2011: In what turned out to be his final game with the Colts, Manning was 18-of-26 for 225 yards and a touchdown in a playoff loss to the New York Jets.

Sept. 8, 2011: The Colts announced that Manning would be out two to three months after his second neck surgery in four months. He underwent a procedure to repair a bulging disk and nerve problem in May. Manning missed the entire 2011 season.

March 7, 2012: The Colts announced during an emotional news conference that they were releasing Manning after 13 seasons. He would have been owed a $28 million bonus if he had not been released.