Dallas Cowboys quarterback Tony Romo left Thursday's game against the Carolina Panthers with an injury to his left collarbone and will not return.
Romo was injured in the third quarter after a 10-yard sack by Thomas Davis.
Romo missed seven games with a broken left collarbone suffered in the Week 2 win against the Philadelphia Eagles when linebacker Jordan Hicks landed on Romo after an incomplete pass.
Davis landed on Romo on this sack, jamming Romo's left shoulder into the turf.
After getting treated by the Cowboys' medical staff Romo went straight to the locker room for further examination. He was holding his left arm close to his side as he walked off the field.
Romo did not have surgery and returned to action last week against the Miami Dolphins.
Romo's Thanksgiving could not have been worse. He was intercepted three times in the first half and had two of them returned for touchdowns by Kurt Coleman and Luke Kuechly.
It is the fourth time in his career he has had two interceptions returned for touchdowns in a game in his career.
Romo missed the final 10 games of the 2010 season because of a broken left collarbone suffered on a hit by New York Giants linebacker Michael Boley. Matt Cassel replaced Romo.
The Cowboys released Brandon Weeden on Nov. 17. They have Kellen Moore and Jameill Showers on the practice squad.