Henderson made the statement Thursday night during Spike TV's "MMA Uncensored Live."
UFC, however, has yet to make an official announcement regarding a fight between Henderson and Machida.
A win over Machida could land Henderson a 205-pound title shot. He was slated to face current champion Jon Jones on Sept. 1 at UFC 151 in Las Vegas, but an injury forced Henderson (29-8) to withdraw from the fight. UFC 151 would be cancelled after Jones refused to fight Henderson’s replacement, Chael Sonnen, on eight days’ notice. Machida turned down an opportunity to salvage the event, citing a lack of time to prepare.
Jones and Sonnen are slated to coach opposite one another on the upcoming season of "The Ultimate Fighter," with Hendo serving as an assistant coach to Sonnen. Jones and Sonnen are scheduled to fight on April 27 in Newark, N.J.
Henderson, who is currently riding a four-fight win streak, has held 205-pound titles in Strikeforce and Pride. He also once held the Pride 170-pound championship.
Machida, who is a former UFC light heavyweight champion, rebounded from a submission loss to Jones at UFC 140 with a second-round knockout of Ryan Bader on Aug. 4. He is 18-3 professionally.