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Viewer's guide: Wake Forest-Syracuse kicks off ACC play in Week 2

Here is a quick rundown of the ACC schedule Saturday. All times ET.

11:30 a.m.

USF (1-0) at No. 11 Florida State (1-0), ESPN. #USFvsFSU. These two programs have gone in different directions since USF upset the Seminoles in 2009. Florida State goes in as the heavy favorite. Quarterback Everett Golson had a nice debut last week, completing 76 percent of his passes against Texas State, the third-best single-game completion percentage in his career. His four passing touchdowns tied the most in his career (Syracuse 2014).

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Houston (1-0) at Louisville (0-1), ESPN3. #HOUvsLOU. The matchup to watch centers on the quarterbacks: Louisville freshman Lamar Jackson and Houston senior Greg Ward Jr. each had more than 100 yards rushing in Week 1. That running capability when the pocket collapses allowed Louisville coach Bobby Petrino to go with Jackson as his starter for the forseeable future.

12:30 p.m.

Wake Forest (1-0) at Syracuse (1-0), ESPN3. #WAKEvsCUSE. This is an important game for both teams, as they are hoping to avoid the Atlantic Division cellar again. But the Orange go into the game without their two best players on offense: quarterback Terrel Hunt (Achilles) is out for the season and H-back Ervin Phillips (lower-body injury) is out for the game. Will freshman Eric Dungey do enough against a good Wake Forest defense?

Appalachian State (1-0) at No. 12 Clemson (1-0), ESPN3.#APPvsCLEM. Deshaun Watson looked good in his first game back since a torn ACL. In his career, Watson has a Total QBR of 91.4, best among FBS quarterbacks with at least 200 action plays. The Tigers must move on without reliable deep threat Mike Williams, who's out indefinitely with a neck injury. Who will step up in his place?

Howard (0-1) at Boston College (1-0), ESPN3. #HOWvsBC. The Eagles are going to want to work on rushing the ball more consistently in this game behind a young offensive line. Missing Myles Willis (mono) last week, BC averaged 4.2 yards per carry on the ground, down from its 5.3-yard average a year ago. Getting the run game going is critical with Florida State up next.

3:30 p.m.

Tulane (0-1) at No. 15 Georgia Tech (1-0), ESPN3. #TULNvsGT. Here is a good note from ESPN Stats & Information: Tulane has lost 46 straight games against ranked opponents, last beating No. 19 Vanderbilt in 1984. That’s the longest active losing streak against ranked opponents among FBS teams. The Jackets are going to want to be sure they are hitting on all cylinders with a big game against Notre Dame next week.

No. 9 Notre Dame (1-0) at Virginia (0-1), ABC. #NDvsUVA. Virginia faces its second straight Top 25 opponent after losing to UCLA last weekend. The Cavaliers have lost nine straight against top-10 opponents since beating No. 4 Florida State in 2009. Keep an eye on the Notre Dame backfield, which moves on without injured starter Tarean Folston. C.J. Prosise, a one-time Virginia recruit, is expected to carry the load.

Furman (0-1) at Virginia Tech (0-1), ESPN3. #FURvsVT. The Hokies have to avoid a letdown after a tough loss to Ohio State and must do so with Brenden Motley behind center. It might be a good idea to just focus on establishing the run, something that was tough to do last week against an elite Buckeyes front.

6 p.m.

NC Central (1-0) at Duke (1-0), ESPN3. #NCCUvsDUKE. Duke should not have many problems in its home opener. The Blue Devils have averaged 49.3 points in their previous three meetings against NC Central.

North Carolina A&T (1-0) at North Carolina (0-1), ESPN3. #NCATvsUNC. The biggest storyline to watch is how quarterback Marquise Williams responds after throwing three interceptions in the opener against South Carolina. Williams said Peyton Manning was one of several quarterbacks who reached out to him last week with words of advice.

Eastern Kentucky (1-0) at NC State (1-0), ESPN3 #EKYvsNCSU. The Wolfpack looked dominant on offense last week against Troy but gave up way too many big plays on defense for coach Dave Doeren's liking. We likely won't know much more about the Pack after this one.

Pitt (1-0) at Akron (0-1), ESPN3. #PITTvsAKRON. This is a big road test for the Panthers without James Conner. Can freshman Qadree Ollison replicate his 200-yard effort from a week ago against a stronger opponent? The good news is receiver Tyler Boyd returns. Pitt absolutely needs him to bolster their lackluster passing attack in Week 1. Chad Voytik only threw for 72 yards.