The Tigers already had to replace starting All-ACC tackle Brandon Thomas, starting guard Tyler Shatley and 1,000-yard back Roderick McDowell. While Anthony was previously suspended for the opener against Georgia, there are no certainties with the offensive line nor the run game in Week 1.
Especially since Clemson struggled to produce consistency in that area last season. Especially since Clemson will need an effective run game to help take pressure off new starting quarterback Cole Stoudt and a new-look group of receivers against what should be an aggressive Georgia defense with familiar foe Jeremy Pruitt taking charge.
Brooks is the bigger blow in the short-term, because he would have contributed heavily against Georgia. Plus, he was the top returning rusher from a year ago and one of the veterans in the group with experience in big games.
But at least Clemson has the luxury of having depth at the position, a group coach Dabo Swinney and offensive coordinator Chad Morris have talked up since the spring. Conceivably, the Tigers should still be able to play four to five backs once they settle on a rotation and still be just as good as they would have been with Brooks in the mix.
That, of course, is dependent on the offensive line, too.
So in the long term, the Anthony loss could loom much larger. Clemson has little in the way of depth at tackle with Anthony gone. The Tigers will now be relying on Joe Gore, pretty raw at the position with just 124 snaps over the past two seasons, and Isaiah Battle -- who has been banged up during camp. Anthony was listed as the backup to both players.
Gore has been one of the bright spots this fall, and would have most likely started against Georgia with Anthony suspended. But now there is no margin for error moving forward. The hope is that Gore steps into the right tackle spot without any issues. But if either Gore or Battle gets hurt, the Tigers could be in trouble. Kalon Davis, projected to start at guard, has also played some tackle during the fall so he would be one potential option as a backup at the position.
It all adds a bit more intrigue to what happens with Clemson this season.