What it means: Great game as Cam Newton outdueled Tom Brady. Brady brought his "A" game but this was Newton's night. He had some dazzling runs against a defense that couldn't make the stop at the critical time. The Patriots fall to 7-3, and they will look back at some lost opportunities as this game was there for the taking. This was a limited-possession game -- the Patriots had just seven offensive drives -- which magnified mistakes on both sides. The Patriots had more of them early and trailed 10-3 at the half before the teams combined to play an exciting second half. A third-and-1 incomplete pass through the back of the end zone forced the Patriots to settle for a field goal to go up 20-17, which set up the Panthers' game-winning touchdown drive. The Patriots fought to the finish, but their final drive fell short with the clock also working against them. Should a penalty have been called on the final play? Fair question.
Aqib Talib vs. Steve Smith: This was the matchup within the matchup and the win goes to Smith, the Panthers' veteran receiver. The two were jawing from the get-go and had to be separated several times after plays. Talib appeared to lose his cool early. Smith beat Talib for a 42-yard gain down the left side in the first quarter, which was a tone-setter of sorts for a one-on-one battle that was especially fun to watch. Talib ultimately left the game in the fourth quarter with a hip injury and didn't return.
Stock watch: Patriots running back Stevan Ridley's ball-security issues resurfaced. He fumbled on the team's second drive and was kept on the sideline for 18 snaps before the coaches went back to him. Ridley runs hard, but if he continues to struggle holding on to the ball, it will likely lead to a drop in his playing time.
Injuries to monitor: Patriots No. 2 tight end Michael Hoomanawanui left the game in the second quarter with a knee injury and did not return. In his absence, five-year veteran Matthew Mulligan bumped up the depth chart and fullback James Develin was utilized a bit more. Also, as noted above, Talib left with a hip injury in the fourth quarter.
Leg whip by Cannon draws scrutiny: Patriots tight tackle Marcus Cannon's leg whip on Panthers defensive end Charles Johnson, which knocked Johnson out of the game with a knee injury, wasn't penalized. But Cannon will likely hear from the NFL in terms of a fine.
Turnover streak snapped: The Patriots had forced a turnover in 36 straight games entering the night, which was the longest active streak in the NFL, but that came to an end.
What's next: The Patriots return home to host the Denver Broncos on Sunday night. Another Brady versus Peyton Manning matchup will be a top storyline, along with receiver Wes Welker's return to town. Welker sustained a concussion in the Broncos' win over the Chiefs on Sunday and his status will be monitored closely.