They’ll definitely need to show more bite defensively than they have against Drew Brees and the Saints in the past.
Here’s five things to watch for on Sunday:
No more Brees spree: Brees must love facing the Giants. He is 4-0 with 11 touchdowns and no interceptions against Big Blue. In destroying the Giants, 48-27 and 49-24, in the teams' past two meetings, Brees passed for eight touchdowns and had a 143.8 quarterback rating.
Brees' teams have scored no less than 30 points against Tom Coughlin’s squad, and have dropped 45 or more three times on the Giants.
The Giants have to figure out a way to get to Brees, who has thrown seven interceptions -- including two pick-sixes -- in his last two games.
No breakdowns: The Giants' secondary will be put to the test. Corey Webster, Prince Amukamara, Rolle and Stevie Brown will have to find a way to slow down the likes of Jimmy Graham, Marques Colston and Lance Moore.
Any of those three can explode at any given time. If the Giants do as good a job as they did against Green Bay’s aerial attack two weeks ago, Perry Fewell’s defense will be looking very good. But the Giants have to keep New Orleans’ running backs in check.
Elite Eli: The Giants will need Eli Manning to match Brees and put points on the board. The Giants had a great game plan and executed it in the first half against Washington by eating up the clock and moving the ball through the air and the ground.
They just didn’t score enough points. The Giants must score more than 16 to beat New Orleans. Manning has to exploit the league’s last-ranked defense. This is a game in which he will have to get the deep ball going with Hakeem Nicks and Victor Cruz, and take advantage of any mismatches with Martellus Bennett as well.
Feed Bradshaw: Ahmad Bradshaw rushed for 100 yards for only the third time this season on Monday night.
The Giants should keep feeding Bradshaw, who will be facing the league’s worst run defense. New Orleans allows 153.8 rushing yards per game. This could very well be a game where David Wilson’s speed and playmaking ability come in handy. But the Giants will have to make sure to protect Manning against a Saints defense that can be aggressive.
Nasty boys: Rolle wants to see the Giants bring a nastier attitude, a "dog mentality," to the field. The last time he spoke up after a Redskins loss, the Giants won six straight games and won the Super Bowl.
The Giants have four games remaining. The Giants don’t have to win out to win the division. But a loss to the Saints could force them to have to win out with games at Atlanta, at Baltimore and versus Philadelphia remaining.
A win here gives the Giants some much-needed room for error. If getting nasty is what will prevent the Giants from taking the hard road -– something they always seem to take –- then they should listen to Rolle again.