Linebacker Michael Boley (hamstring) and running back Ahmad Bradshaw (foot) did not practice on Wednesday.
Boley was on the bike to start practice but was seen walking without a limp later.
"Right now I’m just trying to take it slow, make sure everything is 100-percent," Boley said. "It’s still early in the week. Have some time to come in, get some rehab, get a lot better. We’ll see [about playing against Philadelphia]."
Cornerback Aaron Ross (quad) practiced. Wide receivers Mario Manningham (knee), Hakeem Nicks (hamstring) and Jerrel Jernigan (hip) also practiced.
Boley sat out the second half of the Giants' 27-20 loss to the Niners on Sunday with a hamstring injury. The Giants have just classified Boley as "day-to-day." Boley is an instrumental piece in the Giants defense as the team's lone every-down linebacker and the player who relays the plays to the defensive huddle.
Bradshaw has been out with a fracture in his foot and has missed the last two games.
Tom Coughlin said rookie cornerback Prince Amukamara's status for Sunday's game remains a work in progress. Amukamara practiced on Wednesday.
"Get Ross back first, get Prince going, advance him further, all those things are very important," Coughlin said.
The Giants also got defensive tackle Jimmy Kennedy back from suspension. The Giants have until Monday to add him to the 53-man roster and would have to make a roster move if they choose to do that.