What it means: The Giants fell to 5-8 with three games left to play and therefore cannot finish with a winning record. Since the Eagles and Cardinals won, this loss eliminated the Giants from playoff contention. Obviously, they hung in longer than could have been expected after starting the season 0-6. But that 0-6 start meant they couldn't afford any more stinkers. And this was a stinker.
Stock watch: Run defense, DOWN. A Giants strength for much of the season, the run defense failed the Giants in this game. They went into the game concerned about Danny Woodhead because he and the manner in which the Chargers use him are different from any running back they'd yet faced. And Woodhead had a big game. But so did Ryan Mathews running between the tackles.
Nicks Watch: Wide receiver Hakeem Nicks, a nonfactor in the passing game for most of this season, had catches of 51, 37 and 28 yards in the game. The middle one was a Hail Mary short of the end zone at the end of the first half. The other two were deep downfield in traffic. Nicks was able to outfight defenders for the ball all three times but still isn't separating from them. He also had a couple of drops on shorter patterns, though each of those seemed to be thrown a bit behind him. And he briefly left the game in the second half with some sort of leg injury. Nicks will be a free agent at the end of the year and is likely in his final month as a Giant.
Tuck Watch: Justin Tuck, also a pending free agent, had two sacks after collecting four last week in Washington and is now up to 8.5 for the season. Unlike Nicks, Tuck appears to be making an inspired case to stay.
Turnover redux: Eli Manning threw his 20th interception of the season and had another potential pick overturned by replay review. The Giants are the only NFL team with at least one turnover in every game this year.
What's next: The Giants return home, where they will host the Seattle Seahawks in a 1 p.m. ET game at MetLife Stadium on Sunday. The Seahawks are tied with the Broncos for the best record in the NFL.