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Valbuena's tiebreaking homer lifts Astros over Orioles 4-3

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Valbuena's solo shot lifts Astros (0:21)

Luis Valbuena's solo home run goes the opposite way and gives the Astros a 4-3 victory over the Orioles. (0:21)

HOUSTON -- Evan Gattis hit a two-run homer and Luis Valbuena had a tiebreaking solo shot in the sixth inning that gave the Houston Astros a 4-3 win over the Baltimore Orioles on Wednesday night.

Baltimore tied the score 3-3 with a two-run sixth, and Valbuena homered for the second straight day with an opposite-field drive, two-out to left-center field off Tyler Wilson (2-3).

Houston starter Collin McHugh yielded three runs and eight hits while fanning a season-high 10 in 5 1/3 innings. Pat Neshek (2-0) got the last two outs of the sixth, and Luke Gregerson allowed one hit in a scoreless ninth for his 10th save in 13 chances.

Wilson allowed four runs -- three earned -- and six hits in six innings, losing his second straight decision.