Here are a few things to keep an eye on during the game:
ANY CARRYOVER? Anthony said on Wednesday that there is no bad blood between him and Garnett, so there shouldn't be any carryover from the Jan. 7 incident. Anthony, who was suspended for his role in the confrontation, insists that he's focused solely on getting payback against the Celtics.
Winning at the TD Garden won't be easy for the Knicks, who have lost 13 straight in Boston.
If there's a time to play the Celtics, though, it's Thursday night. Boston has lost four straight, including double-digit losses to New Orleans and Detroit. The Celts are coming off of a loss to last-place Cleveland on Tuesday.
The Knicks are struggling as well, having lost four of six.
They'd benefit from a more efficient output from Anthony, who is shooting 40 percent from the field in his last five games.
WILL PRIGIONI PLAY? Pablo Prigioni is questionable due to a toe injury. He has not practiced in two days and Mike Woodson says he won't know Prigioni's status until this morning's shootaround. If Prigioni doesn't play, the Knicks will have just one healthy point guard (Jason Kidd).
In recent games, that configuration has led to more isolation sets and less ball movement for the Knicks.
It's also led to a more fatigued Anthony.
In Monday's loss to Brooklyn, Anthony was forced to handle the ball during different portions of the game and suggested afterward that it may have slowed him late in the game. He missed all six of his attempts from the field in the fourth quarter.
RONDO IN THE LINEUP: It will be interesting to see if Woodson turns to Shumpert to stop Rajon Rondo. Rondo did not play in the first Knicks-Celtics game due to suspension. He is a matchup nightmare for the 39-year-old Kidd, so it would make sense for Shumpert to guard the lightning-quick Rondo.
Rondo, like Paul Pierce, has proved to be a Knick-killer, averaging 19.3 points and 11.3 assists in his last seven games against New York.
You can follow Ian Begley on Twitter.