Anthony, who traveled with the Knicks to California, has missed the past three games with a sore and stiff right knee, which he injured March 4 in Cleveland.
According to tweets from writers who are in the Bay Area with the Knicks, Anthony participated in Monday's shootaround and said he will play.
If Melo can't go Monday night, coach Mike Woodson plans to give more minutes to forward Chris Copeland for extra offense. The 28-year-old rookie scored 12 points in only seven fourth-quarter minutes on Saturday night in a win over the Jazz.
"Cope can score the basketball," Woodson said. "On our bench, I need guys that can score. I'm not going to hesitate to throw Cope in because I know he can do that. ... [On Saturday night], I thought he proved a little bit that he deserves to be on the floor."
Anthony is second in the NBA in scoring at 28.2 points per game for the 38-22 Knicks, who have a 2½-game lead over the Nets in the Atlantic Division race.