Chandler is arguably the second-most important Knick behind Carmelo Anthony, so New York can't afford to lose him for a significant amount of time.
Falling apart in the fourth: The Knicks shot just 6-for-21 in an ugly fourth quarter. They closed Charlotte's lead to two points with four minutes to play but missed their next five shots from the field as the Bobcats built a comfortable cushion.
Charlotte snapped a 16-game road losing streak with its win at Madison Square Garden. The Knicks fell to 1-3, two games under .500 for the first time since March 2012.
Off night for Melo: Anthony talked before Tuesday's game about being more aggressive in the fourth quarter. But that approach didn't work out well against Charlotte.
Anthony went 3-for-10 in the final quarter and scored six points. On the season, Anthony is 9-for-31 in the fourth.
Anthony finished the night an unsightly 10-for-28 for 29 points. He entered play shooting 37 percent from the field.
Raymond Felton had 14 points on 6-for-15 shooting but missed all five of his shot attempts in the fourth quarter, including three from beyond the arc.
Bad night for Amar'e:Amar'e Stoudemire struggled to find his rhythm on Tuesday night -- and that's putting it nicely. Stoudemire had five turnovers, two points and three rebounds in 11 minutes against Charlotte.
Stoudemire sat out of Sunday's game against Minnesota as part of the organization's plan to platoon him and Kenyon Martin.
Martin wasn't supposed to play on Tuesday after playing 17 minutes on Sunday. But with Chandler out, Knicks coach Mike Woodson was forced to use Martin. The veteran forward played 18 minutes on Tuesday, blocking two shots and grabbing a rebound.
The Garden crowd seemed to be a bit down on Stoudemire. They booed him at one point and cheered when Martin replaced him in the fourth quarter.
More Metta?Metta World Peace also played more minutes with Chandler out. World Peace had 18 points, six rebounds and three steals in 32 minutes. But he had three turnovers and took a few questionable shots down the stretch. He missed three of four shots in the quarter.
What's next: The Knicks have two days of practice to prepare for Friday's road game against Charlotte.