Rapid Reaction: Yankees 9, Mets 1

Recap | Box score | Photos

WHAT IT MEANS: Mets manager Terry Collins didn’t sleep well after Johan Santana’s career-high 134-pitch no-hitter -- the first no-hitter in franchise history -- last Friday night.

Don’t expect that to change a week later.

In his first start since the no-hitter, Santana, pitching on six days rest, gave up a career-high-tying four home runs and the Mets were walloped by the Yankees, 9-1, in the 2012 Subway Series opener in the Bronx.

Santana’s final line: 5 IP, 7 H, 6 ER, 1 BB, 5 K, 86 pitches (51 strikes)

The southpaw allowed back-to-back-to-back homers for the first time in his career in the third inning. The last Mets pitcher to do so? John Maine on June 12, 2007 in Los Angeles.

Santana (3-3) has given up four homers in a game four times -- the last time on May 2, 2010 in Philadelphia. Coming in, he had given up just four homers all season.

In the new Yankee Stadium, he owns an 0-3 record in three starts (14 IP, 19 ER).

During his career, the 33-year-old ace came in 13-3 with a 3.19 ERA on six days of rest or more.

NO-HAN, NO-MORE: Johnny Vander Meer's record is safe.

Santana’s bid for a second straight no-hitter ended five batters in, when Robinson Cano took him deep for a two-run home run to right after Alex Rodriguez walked to lead off the second inning.

The homer ended the southpaw’s consecutive scoreless inning streak at 19.

Santana had thrown two straight complete-game shutouts. No Mets pitcher has ever tossed three of them in a row.

Cano also took Santana yard for another two-run shot to right in the third. Then Nick Swisher and Andruw Jones followed by drilling bombs to left.

NO NO-NO: Omar Quintanilla broke up Hiroki Kuroda's no-hit bid, doubling into left with two outs in the sixth. It was the only hit the Mets mustered off Kuroda (7 IP, 7 K) all night.

IT’S TIME: Ike Davis struck out twice and grounded to second in his other at-bat. The first baseman is now batting .158. His swing looks broken. A stint in the minors may be exactly what he needs to fix it.

BAY’S BACK: Jason Bay went 0-for-3 in his return to the lineup. He batted eighth and played left field.

RAUCH WATCH: Jon Rauch, following three days of rest due to elbow inflammation, faced the minimum in the eighth.

SEEING YOUR EX: Former Met Ryota Igarashi pitched the ninth and surrendered a two-out RBI double to Lucas Duda.

UP NEXT: Mets at Yankees, Game 2 on Saturday night: Dillon Gee (4-3, 4.48 ERA) versus Phil Hughes (5-5, 4.96).