ESPN

WHAT IT MEANS: Pedro Beato surrendered a two-run double to Ryan Braun and Jason Isringhausen served up a game-tying two-run homer to Prince Fielder later in Milwaukee’s four-run eighth.

The Mets, who had taken a 6-2 lead with a five-run top half of that inning, squandered their largest lead of the season in a defeat. They previously had coughed up a three-run lead against San Francisco in a 7-6, 10-inning loss on May 3.

The final blow Wednesday: Nyjer Morgan's RBI off Dale Thayer in the bottom of the ninth. The Mets suffered their first walk-off loss of the season.

The five-run top of the eighth against reliever Kameron Loe included an RBI double by Carlos Beltran, RBI single by Angel Pagan and three-run homer by Ronny Paulino -- the first long ball of his Mets career. Pagan was starting in the cleanup spot for the first time in his career.

WOLF THE MAN: Randy Wolf still owns the Mets. Wolf fell behind in the fourth inning after plunking Jason Bay with a pitch on the left knee, then eventually letting Bay trot home on the first balk of the southpaw’s 13-year career. But Fielder answered with a two-run homer on a 3-0 pitch from Mike Pelfrey in the bottom half of that inning as Milwaukee took a 2-1 lead.

Fielder’s two-homer game gave him 209 as a Brewer, passing Gorman Thomas for third on that franchise’s all-time list.

Wolf, who departed with a one-run lead, received a no-decision. He was bidding for his seventh straight winning decision against the Mets, which would have matched Roy Halladay for the longest streak among active pitchers. Wolf also was bidding for his 13^th career win against the Mets, which would have matched Tim Hudson and Livan Hernandez for the most by an active pitcher. He also would have joined Ron Villone as the only pitchers to beat the Mets with five different teams, according to the Elias Sports Bureau.

Pelfrey was lifted from the hook after the Mets’ eighth-inning rally. His line: 6 IP, 4 H, 2 ER, 0 BB, 2 K.

0, NO: Bay, despite reaching base on the hit-by-pitch, went 0-for-3 and is hitless in his last 23 at-bats. Nick Evans, meanwhile, went 0-for-3. The righty-hitting Evans struck out twice and grounded into a double play as the starter at first base against the southpaw Wolf. Evans is hitless in 12 at-bats in the majors this season. The Brewers’ Casey McGehee snapped an 0-for-27 skid with a seventh-inning single off Bobby Parnell.

STREAKING: Jose Reyes opened the game with a double, extending his hitting streak to 12 games.

K-ROD TRACKER: Francisco Rodriguez did not appear and remained at 24 games finished. He is on pace for 64 games finished, nine over the threshold for his contract to vest at $17.5 million for 2012.

WHAT’S NEXT: Jon Niese (4-5, 3.75 ERA) opposes Yovani Gallardo (8-2, 3.72) in Thursday’s 8:10 p.m. ET rubber game. Gallardo has won his last six starts.