Jan. 3, 1920: The Yankees purchase the contract of Babe Ruth from the Boston Red Sox for $125,000 and a $350,000 loan against the mortgage on Fenway Park.

Sept. 28, 1923: The Yankees record 30 hits in a 24-4 rout of the Red Sox. The hit total remains the most in a nine-inning game in Yankees history, while the 24 runs are the second-most ever by the club in an away game -- and their most ever at Fenway.

Sept. 8, 1925: Babe Ruth hits his 300th career home run off Buster Ross in a 7-4 Yankees victory.

June 23, 1927:In an 11-4 Yankees victory, Lou Gehrig becomes the first player in franchise history to hit three homers in a game against the Red Sox. The feat would be matched by Mark Teixeira on May 8, 2010, also at Fenway Park.

Sept. 5, 1927: In the first game of a doubleheader, the Yankees lose, 12-11, in 18 innings in the second-longest road game in franchise history (in terms of innings played). The Yankees score two runs in the top of the ninth to send it to extra innings and both teams score three runs in the 17th inning. Red Sox pitcher and future Yankees ace Red Ruffing goes 15 innings in the start.

July 3, 1932: The Yankees rout the Red Sox, 13-2, in the first ever Sunday game at Fenway Park. Sunday baseball had actually been approved in Boston three years earlier, but was not played at Fenway due to its proximity to a church. The Sox played their Sunday games at Braves Field on Commonwealth Avenue until the law was amended.

June 6, 1934: Myril Hoag goes 6-for-6 in a 15-3 win in game one of a doubleheader, becoming the first Yankee to go 6-for-6 in a nine-inning game. The feat was later equalled by Johnny Damon on June 7, 2008 against the Royals.

Sept. 22, 1935: The Yankees sweep a doubleheader from the Red Sox, 9-0 and 6-4, in front of 47,267 fans -- the largest crowd to ever see a baseball game at Fenway.

July 9, 1946: In the first-ever All-Star Game hosted at Fenway, the Yankees’ Charlie Keller hits a two-run homer in the first inning of a 12-0 American League victory.

April 18, 1950: On Opening Day, the Yankees overcome a 9-0 deficit to win 15-10 at Fenway Park, scoring 11 runs over the final two innings. The win matches their largest deficit overcome in a road win in franchise history.

April 14, 1955: Elston Howard becomes the first black player in Yankees history, making his major-league debut in an 8-4 loss at Fenway. He records an RBI single in his only plate appearance.

Sept. 21, 1956: In a 13-7 Yankees loss at Fenway Park, Mickey Mantle hits what is considered the longest known homer to straightaway center field in Fenway Park history. The second-inning solo homer off Frank Sullivan carries approximately 480 feet before it struck one foot below the top brick barrier located behind section 36.

July 21, 1961: The Yankees score five runs in the top of the ninth to come back for an 11-8 win at Fenway Park. The big blow: a pinch-hit, grand slam homer byJohnny Blanchard off Mike Fornieles.

Sept. 11, 1966: Johnny Miller makes his big league debut, homering in his first plate appearance in the second inning off Lee Stange in the Yankees 4-2, 10-inning win. Bobby Richardson hits a two-run homer in the 10th to give the Yankees the win.

April 6, 1973: The Yankees’ Ron Blomberg becomes the major league's first first designated hitter. Batting in the top of the first inning, he walks with the bases loaded off Luis Tiant and finishes the day 1-for-3 with 1 RBI in the 15-5 loss.

Oct. 2, 1978: The Yankees defeat the Red Sox, 5-4, in only the second one-game playoff in AL history. Bucky Dent breaks the Red Sox' backs with a three-run, seventh-inning home run, in one of the most memorable homers in baseball history.

June 19, 2000: The Yankees humiliate the Sox, 22-1, with five different Yankees homer in the game, including Jorge Posada,who also scored four runs in the contest. Chuck Knoblauch is the only Yankees starter without a hit in the game. The Yankees score a combined 16 runs over the final two innings, including seven in the ninth off Tim Wakefield.

Sept. 2, 2001: Mike Mussina beats the Red Sox 1-0 and comes within one out of a perfect game as Carl Everett singles with two outs in the ninth.

Oct. 16-18, 2004: The Yankees win Game 3 of the ALCS, 19-8, at Fenway Park to go up 3-games-to-none … Boston would win the next two nights at Fenway Park with consecutive extra-inning walk-off wins and go on to become the first team to overcome a 3-games-to-none deficit in a best-of-seven series.

Aug. 18, 2006: In the second game of a doubleheader, the Yankees beat the Red Sox 14-11 in the longest nine-inning game (4 hours, 45 minutes) in major-league history. That marathon followed the Yanks' 12-4 rout of the Sox that zipped along at 3:55. The Yankee sweep kicks off a nightmarish weekend for the Red Sox, who lose a five-game series to the Bombers.

April 22, 2007: In a 7-6 defeat, Yankees starter Chase Wright surrenders four consecutive home runs in the third inning to Manny Ramirez, J.D. Drew, Mike Lowell and Jason Varitek. The lefthander became just the second big league pitcher ever to allow four consecutive home runs in an inning, joining the Los Angeles Angels' Paul Foytak, who did it in the sixth inning of a July 1, 1963 game against Cleveland (credit: Elias Sports Bureau).

Sept. 28, 2008: On the final day of the season -- and what turns out to be his final career outing -- Mussina becomes a 20-game winner for the first time in his career, reaching the plateau in a 6-2 win in the first game of a doubleheader at Fenway.

(h/t to Yankees PR)