Feeling good: The Bills are not a good defense against the run, allowing 136 yards per game on the ground to opponents. The Redskins' offense operates best when it's committed to the run. Even with starting running back Tim Hightower out for the season, they have two backs in Ryan Torain and Roy Helu who should be able to pile up yards and help them control the clock against the Bills.
Cause for concern: Buffalo doesn't yield many sacks, as quarterback Ryan Fitzpatrick is good at getting rid of the ball quickly and Chan Gailey has excelled at designing protections for him. So a Washington defense that's been shaky against the run and relies on getting to the quarterback could struggle if it doesn't find a way to contain star Buffalo running back Fred Jackson. The Redskins are leaning on their defense more than ever now with all of those offensive starters down with injuries. They'll need to limit Buffalo's scoring to have a chance.