Ansah tested the ankle during warm-ups before the game, but had only practiced one day in the past two weeks and appeared unlikely to play from the start. Rookie Devin Taylor will make his second career start in place of Ansah.
Burleson had hinted he likely wasn't going to play this week as well, but he warmed up before the official no-go decision was made.
In bigger news for the Lions, Steelers linebacker LaMarr Woodley was deemed inactive. That's a big deal for Detroit, which will start rookie right tackle LaAdrian Waddle for the third straight game. Facing Woodley would have been the biggest test so far for Waddle.