It’s a natural because the Saints are hosting the New York Giants. Manning played quarterback for the Saints and raised two NFL quarterbacks, who grew up in New Orleans.
Youngest son Eli Manning will be the starting quarterback for the Giants. The Saints initially had two games scheduled that would have involved ties to the Mannings. But that didn’t work out. Indianapolis quarterback Peyton Manning has been out all season with a neck injury. The Saints defeated the Colts at home earlier this season.