SANTA CLARA, Calif. -- It appears Mario Manningham could miss his second straight game Sunday at Arizona.
Manningham did not practice Thursday because of a lingering knee issue. He didn't play Monday. Rookie Quinton Patton, who was out since Week 4 when he broke his foot, took Manningham's place.
That could be the case Sunday at Arizona. Manningham was on the field during warm-ups but went to work with a trainer when practice began. He came back at the midway point after being out since last December with a knee issue.
“He's just working through something and just felt it was best to help tend to it that way,” San Francisco offensive coordinator Greg Roman said Thursday when asked about Manningham not playing Monday.
Manningham, a free agent at the end of the season, has done very little in the four games Michael Crabtree has been back. So, if his injury lingers it may behoove the 49ers to continue to look at a youngster like Patton since he is guaranteed to be with the team next year.