That was the most notable pregame roster move for San Francisco in Week 11. The team also declared free safety Madieu Williams inactive, choosing instead to keep cornerback Shawntae Spencer active. Spencer provides additional coverage depth after starter Tarell Brown suffered a knee injury in practice. The team listed Brown as questionable. He is active. Also at corner, rookie Chris Culliver is coming off a rough week against the New York Giants, according to 49ers' coaches.
The Arizona Cardinals' inactive list featured no big surprises. Quarterback Kevin Kolb and tight ends Todd Heap and Rob Housler will miss the game while resting injuries. All have struggled with injuries in recent weeks. Kolb in particular was not expected to play.