- Mike Sando, NFL Insider
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Arizona Cardinals: Life without the injured Ryan Williams at running back begins Sunday against a Buffalo defense that allowed 621 yards to San Francisco, including 311 on the ground. Utility back LaRod Stephens-Howling expects to return from a hip injury. He was limited Wednesday. Arizona will presumably incorporate Stephens-Howling into its no-huddle offense and into its spread passing sets. He's not an every-down back, but when healthy, Stephens-Howling provides big-play ability in doses. The Cardinals did not sign a veteran back after losing Williams (for the season) and would-be starting back Beanie Wells (until Nov. 25). William Powell and Alfonso Smith are the leading candidates to carry the ball on early downs. Defensive end Darnell Dockett (hamstring) played sparingly in Week 5 and was limited Wednesday. Tight end Todd Heap practiced on a limited basis. A knee injury has kept Heap out for the past three games. Cornerback Greg Toler, who pulled up with a hamstring injury while allowing a touchdown pass at St. Louis, did not practice. Cornerback Michael Adams also missed practice with a hamstring injury. The Cardinals figure to need their cornerbacks against Buffalo, a team that uses three-plus receivers extensively. Fullback Anthony Sherman (22 snaps at St. Louis) and outside linebacker Quentin Groves (six snaps) also sat out. Sherman has a knee injury. Groves has a hamstring injury. Quarterback John Skelton is back from his ankle injury, but he's not full strength. Kevin Kolb remains the starter.
St. Louis Rams: Leading receiver Danny Amendola will miss roughly six weeks, beginning with St. Louis' game at Miami. That will probably affect the Rams' ability to throw quickly and productively against pressure, and to convert on third down. Amendola ranks third in the NFL behind Wes Welker and Victor Cruz with 24 receptions from the slot. He made eight of those receptions on third down. Safety Quintin Mikell practiced without limitation Wednesday less that a week after suffering a concussion against Arizona. Linebacker Mario Haggan (thigh), fullback Brit Miller (ankle) and left tackle Rodger Saffold (knee) did not practice. Saffold has missed three games and was expected to miss at least four. Defensive linemen William Hayes (back) and Eugene Sims (head), key contributors both, were limited in practice.
San Francisco 49ers: Coach Jim Harbaugh and quarterback Alex Smith told reporters they're not concerned about the injury Smith suffered to the middle finger on his throwing hand. The injury did not appear serious, but it was initially a concern. This could be the week San Francisco debuts running back Brandon Jacobs, who has not played since suffering a knee injury during camp. Letting Jacobs suit up against the New York Giants, his former team, would seem fitting. The 49ers are getting good play from their existing backs, however, and Jacobs doesn't offer much on special teams. One question is whether the 49ers could use Jacobs in short-yardage situations. Frank Gore has two first downs on six third-and-1 carries this season. Anthony Dixon has one first down (a touchdown) on his only third-and-1 carry. Gore converted the team's only fourth-and-1 rush. Add it up and San Francisco has converted four times in eight short-yardage chances, the same figures Jacobs posted with the Giants during the 2011 regular season.
Seattle Seahawks: Center Max Unger will join the injury report for Seattle this week with a hip injury that was expected to keep him from practicing Wednesday. Former starting guard John Moffitt, a contingency at center when healthy, was also among those missing practice. A knee injury will keep him inactive this week. Eight players have started on the offensive line for Seattle this season, tied with Jacksonville for most in the league. Seattle does have options at center. Lemuel Jeanpierre has started there. Defensive linemen Clinton McDonald (groin) and Jaye Howard (foot) did not practice. The team continues to list running back Marshawn Lynch as limited with a back injury. He has 121 touches this season, second-most in the NFL behind Arian Foster (142). Lynch had 313 touches last season.
Arizona Cardinals: Life without the injured Ryan Williams at running back begins Sunday against a Buffalo defense that allowed 621 yards to San Francisco, including 311 on the ground.