- Mike Sando, NFL Insider
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With Arizona and San Francisco set to kick off Monday night, a few notes recalling what happened the last time the Cardinals and 49ers clashed at University of Phoenix Stadium:
The 49ers lost left tackle Joe Staley to a concussion. Center Jonathan Goodwin suffered through an uncharacteristically rough game as San Francisco had trouble offensively. This time, San Francisco's line is coming off one of its best games.
Cardinals quarterback Kevin Kolb left the game with a concussion after the first few plays. Backup John Skelton narrowly escaped a crushing blow on a rushing attempt. 49ers quarterback Alex Smith took five sacks and finished with a season-low 7.7 Total QBR score.
Arizona's offense kept exploiting the middle of the field. The Cardinals completed 12 passes for 229 yards between the yard-line numbers. The 49ers were missing linebacker Patrick Willis, which did not help, but that couldn't have been the only factor. Skelton completed scoring passes for 60 yards (Early Doucet) and 46 yards (Larry Fitzgerald). There was another 53-yard reception (Fitzgerald). The 49ers have allowed only two pass plays of 40-plus yards this season.
Related: full wrap-up from that game.