Another 49ers player, Kentwan Balmer, is already the highest-drafted member of the 2008 draft not on an 80-man roster. The 49ers placed him on the exempt/left squad list. Balmer does not count against the 80-man limit.
Coffee was the 74th overall choice in 2009. Terrance Taylor, chosen 136th overall by the Indianapolis Colts in 2009, is currently the highest-drafted member of his class not on an active roster. Former 49ers linebacker Scott McKillop, chosen 146th overall, is next on that list after suffering a serious knee injury in camp last week. He was waived/injured.
Limas Sweed, chosen 53rd overall by the Pittsburgh Steelers in 2008, is the highest-drafted player from his class other than Balmer not on an active roster. The Steelers placed him on injured reserve.
Note: Thanks to jamiemiller74 for asking about Balmer's status.