1. Landry and Davis debut: Safety LaRon Landry and cornerback Vontae Davis will play in their first preseason game after missing all of minicamp and almost the first two weeks of training with groin injuries. Outside of possibly the other safety position, the Colts could have their Week 1 starting defense as long as coach Chuck Pagano doesn't decide to rest any players. Delano Howell, who is in the running for the safety position, didn't practice earlier this week because of a neck injury. Landry playing is the first step in him starting his rebound from what was an underachieving first season in Indianapolis. Davis is making his debut after signing a four-year, $39 million contract during the offseason.
2. Jonotthan Harrison at center: The undrafted rookie out of Florida will make his first start in place of the Khaled Holmes (ankle). Harrison had early jitters after replacing Holmes late on the Colts' first drive against the New York Jets on Aug. 7. He had two bad snaps, but settled down after that. Holmes is expected to be back in time for the season opener against Denver, so Harrison needs to use the extra playing time to show the coaching staff that he'll be ready if called upon should Holmes get injured again. Holmes has dealt with injuries to both ankles since being drafted by the Colts in 2013.
3. Race for fourth receiver: Da'Rick Rogers showed he planned to stick around in the race for the fourth receiver spot when he hauled in a 45-yard pass along the sideline against the New York Jets. That was the best play of training camp for Rogers. Donte Moncrief has been leading the race for that spot behind T.Y. Hilton, Reggie Wayne and Hakeem Nicks. You can say the rookie out of Ole Miss has exceeded expectations so far. He's the frontrunner to return kicks for the Colts.