1. The other safety: While a significant number of veterans likely won't play, you can expect to see the players competing for the safety spot alongside of LaRon Landry -- Mike Adams, Sergio Brown and Colt Anderson -- in the lineup. Coach Chuck Pagano said earlier this week that a decision still hasn't been made on who will replace the departed Antoine Bethea at safety. Adams, Brown and Anderson all played in the first half at different times with the starting unit against the New Orleans Saints last weekend. "I think they've all shown signs and played well at times," Pagano said. "Has anybody separated themselves to this point where we're going to go ahead and put our depth chart out? We're not ready to do that yet. Again, they're all doing well and have played well and we'll see where that thing goes." The Colts still don't have a medical update on safety Delano Howell (neck), who spent the majority of the offseason as the leader in the race to start.
2. Who's the fifth receiver? The signs point to the Colts keeping six receivers, but Da'Rick Rogers and Griff Whalen, the likely candidates for that spot, can't take anything for granted in case they have a bigger need at another position on the roster. Whalen has the edge on Rogers if the Colts do decide to keep only five receivers. Rogers has shown flashes in the preseason -- a 45-yard catch against the New York Jets and touchdown against the New York Giants -- and has more potential than Whalen. But Whalen has been more consistent going back to training camp at Anderson (Indiana) University.
3. Center of attention: Center Khaled Holmes' sprained ankle, which happened three weeks ago, has not healed to the point where he can start practicing yet. The Colts said after the injury occurred that they hoped to have him back for their Week 1 game at Denver. That's still their thinking, but undrafted free agent Jonotthan Harrison, who has been starting in Holmes' place, has to maintain the mind frame that he'll be the Week 1 starter and continue to take as many snaps as possible in case Holmes doesn't play against the Broncos.