INDIANAPOLIS -- San Diego tight end Antonio Gates is active and is expected to start Sunday night against the Colts.
Gates has been dealing with a foot injury that kept him out of the past two games. He had played in 94 straight games.
Receivers Malcom Floyd and Legedu Naanee are also active. They have been dealing with hamstring injuries. They are expected to play a lot along with Vincent Jackson, who is making his season debut after holding out and serving three games on a roster-exemption list.
Rookie tailback Ryan Mathews will miss his second straight game with an ankle injury. His backup Mike Tolbert will start. He had 111 yards against Denver last week. Starting guard Louis Vasquez is out with a neck injury. He will be replaced by Tyronne Green.